27
Feb 2026
Genomic landscape and clinicopathologic significance of POLE mutant colorectal carcinoma
DNA polymerase epsilon catalytic subunit A (POLE) gene plays a crucial role in DNA repair and chromosomal replication.








We are de-risking biomedical innovation, turning biomedical knowledge into social and economic value.
More than three decades later, we remain committed in pursuit of pharmaceutical innovation, providing high quality products and striving to deliver superior business results.
The patient is at the heart of what we do, making decisions regarding biometric innovation is usually a complicated and chaotic procedure as it consists of various product options, various facets to ascertain these on, and multiple evaluations at all levels.
Discover our therapeutic areas, where we continuously invest to innovate and deliver therapeutic solutions for patient’s benefit.
With tailor-made research projects, we provide insights into what works, for whom, at what cost, and under what circumstances to achieve objectives, such as improved healthcare quality, health outcomes, efficiency and staff satisfaction, we support our clients in making evidence-based decisions.
The process of bringing your healthcare innovation to the market is lengthy and complicated. Besides the clinical or humanistic value that your product generates, for example by decreasing complication rate, prolonging survival, improving patient flow, the economic value needs to be demonstrated to healthcare payers.
We help you prepare yourself for (future) discussions with stakeholders about your innovations. During a 1,5 h discussion, we advise you on how to collect, analyse and present data.
Clinical trials are very important as it allow us to evaluate the effectiveness of new drugs, new devices, preventative strategies or treatment strategies. It also enables us to discover better ways for patients' care.
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Our mission remains constant as we endeavor to deliver novel medicines to patients with cancer, treating solid tumors with high unmet medical needs in well-defined patient populations that are currently not well supported.
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Whether you're looking to manufacture toxicology batches or cGMP material for clinical trials, we can help you expedite molecules to clinic with full transparency.
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27
Feb 2026
DNA polymerase epsilon catalytic subunit A (POLE) gene plays a crucial role in DNA repair and chromosomal replication.
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27
Feb 2026
Scientists meeting at Center for BrainHealth during its annual BrainHealth Week conference announced the launch of the Society for Brain Health.
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27
Feb 2026
The World Health Organization (WHO) today announced recommendations for the viral composition of influenza (or "flu") vaccines for the 2026-2027 northern hemisphere influenza season.
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27
Feb 2026
The World Health Organization (WHO) has certified Denmark for the elimination of mother-to-child transmission (EMTCT) of HIV and syphilis, recognizing the country's sustained commitment to ensuring every child is born free of these infections.
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