Mercury Pharmaceuticals

We are de-risking biomedical innovations, while turning biomedical knowledge into social and economic value.

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AI redesign helps enzymes evolve beyond natural limits

24

Jul 2026

AI redesign helps enzymes evolve beyond natural limits

Researchers showed that AI-redesigned botulinum neurotoxin proteases provided more stable starting points for directed evolution, allowing enzymes to access beneficial mutations that were poorly tolerated in wild-type backgrounds. In BoNT/E models, the approach improved activity, evolvability, and specificity, including an ataxin-2-targeting variant with markedly reduced cleavage of the native SNAP25 substrate.

Two heart nerve cell types sustain cardiac stability in mice

23

Jul 2026

Two heart nerve cell types sustain cardiac stability in mice

Researchers identified two major intrinsic cardiac neuron populations in mice: Npy-positive neurons regulate parasympathetic heart rate control and support coronary perfusion, while Ddah1-positive neurons help maintain electrical stability during extreme stress. Removing Npy-positive neurons caused fatal cardiac failure, whereas loss of Ddah1-positive neurons increased susceptibility to malignant arrhythmias and sudden cardiac arrest under stress.

MERCURY trials

Clinical trials are very important as it allow us to evaluate the effectiveness of new drugs, new devices, preventative strategies or treatment strategies. It also enables us to discover better ways for patients' care.
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Cancer

Our mission remains constant as we endeavor to deliver novel medicines to patients with cancer, treating solid tumors with high unmet medical needs in well-defined patient populations that are currently not well supported.
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Neuroscience

Whether you're looking to manufacture toxicology batches or cGMP material for clinical trials, we can help you expedite molecules to clinic with full transparency.
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Mercury Pharmaceuticals

Why Us?

Strong experience in academic research and technology transfer makes us understand your goals and motivations as a technology originator.
Our experience in drug development from discovery to clinical and commercial stages makes us an insider player within the biopharmaceutical industry.
Smart approach to project management that helps speed up development stages and decision making.
Availability of own investment up to 2m€ per project allows us to reach the next value milestone.