22
May 2026
People with opioid use disorder (OUD) are at increased risk of contracting human immunodeficiency virus (HIV). While there are effective interventions that can substantially reduce HIV incidence and opioid overdose, like pre-exposure prophylaxis (PrEP) and medications for opioid use disorder (MOUD), many patients still face barriers to accessing and staying engaged in care.
22
May 2026
Among the younger part of the population, sleep problems, anxiety, and depression are widespread and growing issues.
22
May 2026
Researchers found that more than half of urban rats sampled from low-income communities in Salvador, Brazil, carried active pharmaceutical ingredients in their brain tissue. These pollutants were associated with altered zoonotic infection patterns, including lower Leptospira infection probability in rats carrying azithromycin and higher Capillaria infection probability in rats carrying citalopram.
22
May 2026
Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the functional genome, the working portion of our DNA that helps make each person unique. Put simply, a single gene can be edited in different ways to produce multiple sets of instructions.
22
May 2026
AI-driven genomic analysis could help researchers identify existing drugs that may be repurposed for subtype-specific breast cancer treatment. The review proposes an interpretability-driven framework that links multi-omics data, mechanistic validation, and clinical translation to make AI predictions more transparent and clinically useful.
22
May 2026
A small proof-of-concept RCT found that tocilizumab, an IL-6 receptor blocker, showed a non-significant but clinically suggestive pattern of improvement in difficult-to-treat depression linked to low-grade inflammation. The study found that baseline hs-CRP, rather than IL-6, may help identify patients most likely to respond, supporting larger trials of immune-targeted depression care.
22
May 2026
Younger generations appear to be experiencing poorer health earlier in life than previous generations, according to a review of studies comparing national birth cohort datasets involving tens of thousands of people across the UK born since 1946.
22
May 2026
Not all broken genes fail in the same way: some simply stop working, while others interfere with what still works.
22
May 2026
A new preclinical study led by researchers at The University of Texas MD Anderson Cancer Center and Weill Cornell Medicine has uncovered genetic and cell-state adaptive mechanisms that drive resistance to KRAS inhibitors in patients with KRAS-mutant colorectal cancer.
22
May 2026
An 8-month low-calorie diet plus behavioral support helped older adults with overweight or obesity and persistent atrial fibrillation lose weight safely, with no intervention-related serious adverse events. However, the LOSE-AF trial found no meaningful improvement in AF symptoms, rhythm control, AF burden, cardiac remodeling, or further AF procedure rates compared with usual care.
Clinical trials are very important as it allow us to evaluate the effectiveness of new drugs, new devices, preventative strategies or treatment strategies. It also enables us to discover better ways for patients' care.
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