11
Jun 2026
A novel study among Indigenous communities in Canada utilizing sharing circles as the primary method of qualitative data collection shows that heart health is shaped by emotional, spiritual, social, and systemic factors, with trauma strongly influencing how care is accessed and trusted.
11
Jun 2026
A research team in Japan has developed an efficient and minimally invasive cancer detection device that uses high-performance zinc oxide nanowires to selectively capture extracellular vesicles (EVs) from bodily fluids.
11
Jun 2026
A US cause-specific modeling study found no net protective health effect from low-level alcohol consumption, with lifetime alcohol-attributable mortality risk rising above 1 in 1,000 at just over 6.5 drinks per week for males and 7.0 drinks per week for females.
11
Jun 2026
Researchers found that KAT7 promotes CMPK2-driven mitochondrial DNA release in microglia, activating inflammatory cGAS-STING and NLRP3 pathways linked to Alzheimer’s disease.
10
Jun 2026
The cGAS-STING pathway is emerging as a key driver of chronic neuroinflammation through its effects on glial activation, neuronal stress, blood-brain barrier integrity, and type I interferon signaling. The review highlights why selective, context-dependent modulation of cGAS-STING could help treat neurodegenerative diseases, while preserving its essential roles in antiviral defense and tumor surveillance.
10
Jun 2026
A JCI study found that exposure to a Western diet in mice and to palmitic acid in murine and ex vivo human enteric nervous system models triggered ferroptosis, characterized by iron loading, lipid peroxidation, mitochondrial stress, and enteric neuronal loss. Boosting Nrf2 signaling protected enteric neurons and prevented Western diet-induced delayed colonic transit in mice, pointing to a potential pathway linking dietary fat exposure to gut motility dysfunction.
10
Jun 2026
An unexpected lab observation led a team of scientists to discover how diet can influence survival in animal models of glioma, one of the most aggressive and deadly forms of brain cancer.
10
Jun 2026
A new report in the American Journal of Human Genetics describes a novel disorder caused by biallelic loss-of-function variants in the TMEM63B gene, which results in severe lung disease.
10
Jun 2026
Sjögren's disease is a widespread chronic autoimmune disorder that attacks the body's own glands, yet its underlying disease mechanisms remain poorly understood.
10
Jun 2026
Zang and O’Brien’s Science Perspective highlights evidence that the post-pandemic rise in remote work has increased time spent alone and contributed to higher psychological distress among US workers. Drawing on findings from Emanuel et al., the article argues that workplaces provide an overlooked form of social infrastructure, making hybrid scheduling and institutional support important for preserving flexibility without deepening isolation.
Clinical trials are very important as it allow us to evaluate the effectiveness of new drugs, new devices, preventative strategies or treatment strategies. It also enables us to discover better ways for patients' care.
- Learn more
Our mission remains constant as we endeavor to deliver novel medicines to patients with cancer, treating solid tumors with high unmet medical needs in well-defined patient populations that are currently not well supported.
- Learn more
Whether you're looking to manufacture toxicology batches or cGMP material for clinical trials, we can help you expedite molecules to clinic with full transparency.
- Learn more
