15
Sep 2026
Why frailty and heart health may be more closely connected than we thought
A narrative review proposes cardiovascular frailty as a distinct phenotype that brings together blood pressure regulation, vascular aging, oxi-inflammaging, and clinical frailty deficits. The authors argue that a validated cardiovascular frailty index could support earlier detection and personalized care, although longitudinal studies are needed before the concept can be used clinically.